Tumor Vascular Targeted Delivery of Polymer-conjugated Adenovirus Vector for Cancer Gene Therapy

Previously, we generated a cancer-specific gene therapy system using adenovirus vectors (Adv) conjugated to polyethylene glycol (Adv-PEG). Here, we developed a novel Adv that targets both tumor tissues and tumor vasculatures after systemic administration by conjugating CGKRK tumor vasculature homing...

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Hlavní autoři: Yao, Xinglei, Yoshioka, Yasuo, Morishige, Tomohiro, Eto, Yusuke, Narimatsu, Shogo, Kawai, Yasuaki, Mizuguchi, Hiroyuki, Gao, Jian-Qing, Mukai, Yohei, Okada, Naoki, Nakagawa, Shinsaku
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2011
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182347/
https://ncbi.nlm.nih.gov/pubmed/21673661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.112
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