Neural Stem Cell-based Cell Carriers Enhance Therapeutic Efficacy of an Oncolytic Adenovirus in an Orthotopic Mouse Model of Human Glioblastoma

The potential utility of oncolytic adenoviruses as anticancer agents is significantly hampered by the inability of the currently available viral vectors to effectively target micrometastatic tumor burden. Neural stem cells (NSCs) have the ability to function as cell carriers for targeted delivery of...

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Detalhes bibliográficos
Main Authors: Ahmed, Atique U, Thaci, Bart, Alexiades, Nikita G, Han, Yu, Qian, Shuo, Liu, Feifei, Balyasnikova, Irina V, Ulasov, Ilya Y, Aboody, Karen S, Lesniak, Maciej S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182345/
https://ncbi.nlm.nih.gov/pubmed/21629227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.100
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