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Amyloid in neurodegenerative diseases: Friend or foe?

Accumulation of amyloid-like aggregates is a hallmark of numerous neurodegenerative disorders such as Alzheimer’s and polyglutamine disease. Yet, whether the amyloid inclusions found in these diseases are toxic or cytoprotective remains unclear. Various studies suggest that the toxic culprit in the...

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Detalhes bibliográficos
Main Authors: Wolfe, Katie J, Cyr, Douglas M
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182296/
https://ncbi.nlm.nih.gov/pubmed/21458579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2011.03.011
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