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Glioma Cell Migration on Three-dimensional Nanofiber Scaffolds Is Regulated by Substrate Topography and Abolished by Inhibition of STAT3 Signaling

A hallmark of malignant gliomas is their ability to disperse through neural tissue, leading to long-term failure of all known therapies. Identifying new antimigratory targets could reduce glioma recurrence and improve therapeutic efficacy, but screens based on conventional migration assays are hampe...

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Detalhes bibliográficos
Main Authors: Agudelo-Garcia, Paula A, De Jesus, Jessica K, Williams, Shante P, Nowicki, Michal O, Chiocca, Ennio Antonio, Liyanarachchi, Sandya, Li, Pui-Kai, Lannutti, John J, Johnson, Jed K, Lawler, Sean E, Viapiano, Mariano S
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182275/
https://ncbi.nlm.nih.gov/pubmed/21969816
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