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Obesity Risk Gene TMEM18 Encodes a Sequence-Specific DNA-Binding Protein

Transmembrane protein 18 (TMEM18) has previously been connected to cell migration and obesity. However, the molecular function of the protein has not yet been described. Here we show that TMEM18 localises to the nuclear membrane and binds to DNA in a sequence-specific manner. The protein binds DNA w...

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Autori principali: Jurvansuu, Jaana M., Goldman, Adrian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182218/
https://ncbi.nlm.nih.gov/pubmed/21980424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025317
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