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Vaccinia extracellular virions enter cells by macropinocytosis and acid-activated membrane rupture

Vaccinia virus (VACV), the model poxvirus, produces two types of infectious particles: mature virions (MVs) and extracellular virions (EVs). EV particles possess two membranes and therefore require an unusual cellular entry mechanism. By a combination of fluorescence and electron microscopy as well...

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Detalhes bibliográficos
Main Authors: Schmidt, Florian Ingo, Bleck, Christopher Karl Ernst, Helenius, Ari, Mercer, Jason
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3181475/
https://ncbi.nlm.nih.gov/pubmed/21792173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.245
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