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The miR-17-92 MicroRNA Cluster Is Regulated by Multiple Mechanisms in B-Cell Malignancies

A cluster of six microRNAs (miRNAs), miR-17-92, is processed from the transcript of C13orf25, a gene amplified in some lymphomas and solid tumors. We find that levels of the miRNAs in the cluster do not vary entirely in parallel with each other or with the primary RNA in B-cell lines or normal cells...

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Detalhes bibliográficos
Main Authors: Ji, Ming, Rao, Enyu, Ramachandrareddy, Himabindu, Shen, Yulei, Jiang, Chunsun, Chen, Jianxiu, Hu, Yiqiao, Rizzino, Angie, Chan, Wing C., Fu, Kai, McKeithan, Timothy W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3181398/
https://ncbi.nlm.nih.gov/pubmed/21806958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.06.008
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