Impaired CD4 T Cell Memory Response to Streptococcus pneumoniae Precedes CD4 T Cell Depletion in HIV-Infected Malawian Adults

OBJECTIVE: Invasive pneumococcal disease (IPD) is a leading cause of morbidity and mortality in HIV-infected African adults. CD4 T cell depletion may partially explain this high disease burden but those with relatively preserved T cell numbers are still at increased risk of IPD. This study evaluated...

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Main Authors: Glennie, Sarah J., Sepako, Enoch, Mzinza, David, Harawa, Visopo, Miles, David J. C., Jambo, Kondwani C., Gordon, Stephen B., Williams, Neil A., Heyderman, Robert S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3181344/
https://ncbi.nlm.nih.gov/pubmed/21980502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025610
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