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Identification and Functional Clustering of Genes Regulating Muscle Protein Degradation from amongst the Known C. elegans Muscle Mutants

Loss of muscle mass via protein degradation is an important clinical problem but we know little of how muscle protein degradation is regulated genetically. To gain insight our labs developed C. elegans into a model for understanding the regulation of muscle protein degradation. Past studies uncovere...

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Hlavní autoři: Shephard, Freya, Adenle, Ademola A., Jacobson, Lewis A., Szewczyk, Nathaniel J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3181249/
https://ncbi.nlm.nih.gov/pubmed/21980350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024686
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