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Histopathological Changes and Clinical Responses of Buruli Ulcer Plaque Lesions during Chemotherapy: A Role for Surgical Removal of Necrotic Tissue?

BACKGROUND: Buruli ulcer (BU) caused by Mycobacterium ulcerans is a necrotizing skin disease usually starting with a subcutaneous nodule or plaque, which may ulcerate and progress, if untreated, over months and years. During the currently recommended antibiotic treatment with rifampicin/streptomycin...

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Main Authors: Ruf, Marie-Thérèse, Sopoh, Ghislain Emmanuel, Brun, Luc Valère, Dossou, Ange Dodji, Barogui, Yves Thierry, Johnson, Roch Christian, Pluschke, Gerd
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3181242/
https://ncbi.nlm.nih.gov/pubmed/21980547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001334
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