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Choosing a Mouse Model: Experimental Biology in Context—The Utility and Limitations of Mouse Models of Breast Cancer
Genetically engineered mice are critical experimental models for the study of breast cancer biology. Transgenic mice, employing strong mammary epithelial promoters to drive oncogenes, develop carcinomas with phenotypes corresponding to the molecular pathway activated. Gene-targeted (knockout) mice,...
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| Materialtyp: | Artigo |
| Språk: | Inglês |
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Cold Spring Harbor Laboratory Press
2011
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| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3181037/ https://ncbi.nlm.nih.gov/pubmed/21646376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a009670 |
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