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Identification, localization, and relative quantitation of pseudouridine in RNA by tandem mass spectrometry of hydrolysis products
The constitutional isomers uridine (U) and pseudouridine (Ψ) cannot be distinguished from each other by simple mass measurements of RNA or its fragments because the conversion of U into Ψ is a “mass-silent” post-transcriptional modification. Here we propose a new mass spectrometry based method for i...
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| Main Authors: | , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Elsevier
2011
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3180913/ https://ncbi.nlm.nih.gov/pubmed/21960742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijms.2010.05.024 |
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