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Kruppel-like factor 5 is Required for Formation and Differentiation of the Bladder Urothelium

Kruppel-like transcription factor 5 (Klf5) was detected in the developing and mature murine bladder urothelium. Herein we report a critical role of KLF5 in the formation and terminal differentiation of the urothelium. The Shh(GfpCre) transgene was used to delete the Klf5(floxed) alleles from bladder...

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Detalhes bibliográficos
Main Authors: Bell, Sheila. M., Zhang, Liqian, Mendell, Angela, Xu, Yan, Haitchi, Hans Michael, Lessard, James L., Whitsett, Jeffrey A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3180904/
https://ncbi.nlm.nih.gov/pubmed/21803035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2011.07.020
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