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On-bead combinatorial synthesis and imaging of CEST-MRI agents to identify factors that influence water exchange
The sensitivity of magnetic resonance imaging (MRI) contrast agents is highly dependent on the rate of water exchange between the inner-sphere of a paramagnetic ion and bulk water. Normally, identifying a paramagnetic complex that has optimal water exchange kinetics is done by synthesizing and testi...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3180893/ https://ncbi.nlm.nih.gov/pubmed/21793515 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja201123f |
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