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Synthesis and properties of oligonucleotides containing 4-thiothymidine, 5-methyl-2-pyrimidinone-1-beta-D(2'-deoxyriboside) and 2-thiothymidine.

Methods are given for the synthesis of derivatives of 4-thiothymidine (4ST), 5-methyl-2-pyrimidinone-1-beta-D(2'-deoxyriboside) (4HT) and 2-thiothymidine (2ST) suitable for incorporation into oligodeoxynucleotides by the cyanoethyl phosphoramidite method. 4HT and 2ST are incorporated with no ba...

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Bibliografski detalji
Glavni autori: Connolly, B A, Newman, P C
Format: Artigo
Jezik:Inglês
Izdano: 1989
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC318087/
https://ncbi.nlm.nih.gov/pubmed/2762115
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