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Exploration of possible binding sites of nanoparticles on protein by crosslinking chemistry coupled with mass spectrometry

For the first time, the possible binding site of nanoparticles on protein was revealed by crosslinking chemistry coupled with mass spectrometry. The peptides locating very close to the polyacrylic acid (PAA)-coated Fe(3)O(4) nanoparticles (NPs) during interaction with human serum albumin (HSA) were...

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Autori principali: Li, Ni, Zeng, Shang, He, Le, Zhong, Wenwan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3180867/
https://ncbi.nlm.nih.gov/pubmed/21870789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac201889j
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