Targeting the Nrf2–Keap1 antioxidant defence pathway for neurovascular protection in stroke

ABSTRACT: Endogenous defence mechanisms by which the brain protects itself against noxious stimuli and recovers from ischaemic damage are a key target of stroke research. The loss of viable brain tissue in the ischaemic core region after stroke is associated with damage to the surrounding area known...

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Main Authors: Alfieri, Alessio, Srivastava, Salil, Siow, Richard C M, Modo, Michel, Fraser, Paul A, Mann, Giovanni E
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2011
Assuntos:
Symposium Section Reviews: Molecular Mechanisms Underlying Neurovascular Protection in Stroke
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3180573/
https://ncbi.nlm.nih.gov/pubmed/21646410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2011.210294
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