Correlation of MGMT promoter methylation status with gene and protein expression levels in glioblastoma

OBJECTIVES: 1) To correlate the methylation status of the O(6)-methylguanine-DNA-methyltransferase (MGMT) promoter to its gene and protein expression levels in glioblastoma and 2) to determine the most reliable method for using MGMT to predict the response to adjuvant therapy in patients with gliobl...

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Bibliografske podrobnosti
Main Authors: Uno, Miyuki, Oba-Shinjo, Sueli Mieko, Camargo, Anamaria Aranha, Moura, Ricardo Pereira, de Aguiar, Paulo Henrique, Cabrera, Hector Navarro, Begnami, Marcos, Rosemberg, Sérgio, Teixeira, Manoel Jacobsen, Marie, Suely Kazue Nagahashi
Format: Artigo
Jezik:Inglês
Izdano: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2011
Teme:
Clinical Science
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3180167/
https://ncbi.nlm.nih.gov/pubmed/22012047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/S1807-59322011001000013
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