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Human nucleotide excision repair in vitro: repair of pyrimidine dimers, psoralen and cisplatin adducts by HeLa cell-free extract.

We searched for nucleotide excision repair in human cell-free extracts using two assays: damage-specific incision of DNA (the nicking assay) and damage-stimulated DNA synthesis (the repair synthesis assay). HeLa cell-free extract prepared by the method of Manley et al. (1980) has a weak nicking acti...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sibghatullah, Husain, I, Carlton, W, Sancar, A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1989
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC318007/
https://ncbi.nlm.nih.gov/pubmed/2748330
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