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Photoaffinity labeling of the multidrug resistance protein 2 (ABCC2/cMOAT) with a photoreactive analog of LTC(4)

Several studies have shown that the multidrug resistant protein MRP2 mediates the transport of chemotherapeutic drugs and normal cell metabolites, including Leukotriene C (LTC(4)); however direct binding of the LTC(4) to MRP2 has not been demonstrated. In this study, a photoreactive analog of LTC(4)...

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Detalhes bibliográficos
Main Authors: Leimanis, Mara L., Karwatsky, Joel, Georges, Elias
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3180033/
https://ncbi.nlm.nih.gov/pubmed/21968553
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