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Novel piperazine induces apoptosis in U937 cells

The effect of 1,4-bis-(4-(1H-benzo[d]imidazol-2-yl-phenyl)) piperazine (BIPP), a newly synthesized piperazine derivative, on U937 leukemia cell viability was investigated. We show that BIPP induces dose-responsive apoptotic cell death in U937 cells by intrinsic mechanisms of apoptosis. Maximum apopt...

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Detalhes bibliográficos
Main Authors: Sampson, Josiah J., Donkor, Isaac O., Huang, Tien L., Adunyah, Samuel E.
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3180031/
https://ncbi.nlm.nih.gov/pubmed/21968418
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