JNK suppression is essential for 17β-Estradiol inhibits prostaglandin E2-Induced uPA and MMP-9 expressions and cell migration in human LoVo colon cancer cells

BACKGROUND: Epidemiological studies demonstrate that the incidence and mortality rates of colorectal cancer in women are lower than in men. However, it is unknown if 17β-estradiol treatment is sufficient to inhibit prostaglandin E2 (PGE2)-induced cellular motility in human colon cancer cells. METHOD...

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Autori principali: Hsu, Hsi-Hsien, Hu, Wei-Syun, Lin, Yueh-Min, Kuo, Wei-Wen, Chen, Li-Mien, Chen, Wei-Kung, Hwang, Jin-Ming, Tsai, Fuu-Jen, Liu, Chung-Jung, Huang, Chih-Yang
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179949/
https://ncbi.nlm.nih.gov/pubmed/21859479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-18-61
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