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A whole blood monokine-based reporter assay provides a sensitive and robust measurement of the antigen-specific T cell response

BACKGROUND: The ability to measure T-cell responses to antigens is proving critical in the field of vaccine development and for understanding immunity to pathogens, allergens and self-antigens. Although a variety of technologies exist for this purpose IFNγ-ELISpot assays are widely used because of t...

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Detalhes bibliográficos
Main Authors: Chakera, Aron, Bennett, Sophia C, Cornall, Richard J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179727/
https://ncbi.nlm.nih.gov/pubmed/21871084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-9-143
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