Kinetics of Ethylene and Ethylene Oxide in Subcellular Fractions of Lungs and Livers of Male B6C3F1 Mice and Male Fischer 344 Rats and of Human Livers

Ethylene (ET) is metabolized in mammals to the carcinogenic ethylene oxide (EO). Although both gases are of high industrial relevance, only limited data exist on the toxicokinetics of ET in mice and of EO in humans. Metabolism of ET is related to cytochrome P450-dependent mono-oxygenase (CYP) and of...

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Bibliografiska uppgifter
Huvudupphovsmän: Li, Qiang, Csanády, György András, Kessler, Winfried, Klein, Dominik, Pankratz, Helmut, Pütz, Christian, Richter, Nadine, Filser, Johannes Georg
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2011
Ämnen:
Biotransformation and Toxicokinetics
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179684/
https://ncbi.nlm.nih.gov/pubmed/21785163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfr194
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