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FDM: a graph-based statistical method to detect differential transcription using RNA-seq data

Motivation: In eukaryotic cells, alternative splicing expands the diversity of RNA transcripts and plays an important role in tissue-specific differentiation, and can be misregulated in disease. To understand these processes, there is a great need for methods to detect differential transcription bet...

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Bibliographic Details
Main Authors: Singh, Darshan, Orellana, Christian F., Hu, Yin, Jones, Corbin D., Liu, Yufeng, Chiang, Derek Y., Liu, Jinze, Prins, Jan F.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179659/
https://ncbi.nlm.nih.gov/pubmed/21824971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btr458
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