Immune Reconstitution in Recipients of Photodepleted HLA-identical Sibling Donor Stem Cell Transplants: T cell Subset Frequencies Predict Outcome

We evaluated an ex-vivo photodepletion technique to selectively deplete graft-versus-host disease (GVHD) alloreacting T cells given to 24 HLA-identical sibling stem cell transplant (SCT) recipients. Donor lymphocytes were activated by 72 hr exposure to irradiated in-vitro expanded recipient T lympho...

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Detalhes bibliográficos
Main Authors: McIver, Z, Melenhorst, JJ, Grim, A, Naguib, N, Weber, G, Fellowes, V, Khuu, H, Stroncek, D, Leitman, S, Battiwalla, M, Barrett, AJ
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179560/
https://ncbi.nlm.nih.gov/pubmed/21684345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2011.05.017
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