Role of Chaperone Mediated Autophagy (CMA) in the Degradation of Misfolded N-CoR Protein in Non-Small Cell Lung Cancer (NSCLC) Cells

Nuclear receptor co-repressor (N-CoR) plays important role in transcriptional control mediated by several tumor suppressor proteins. Recently, we reported a role of misfolded-conformation dependent loss (MCDL) of N-CoR in the activation of oncogenic survival pathway in acute promyelocytic leukemia (...

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Bibliographic Details
Main Authors: Ali, Azhar Bin, Nin, Dawn Sijin, Tam, John, Khan, Matiullah
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179509/
https://ncbi.nlm.nih.gov/pubmed/21966475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025268
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