Substance P Induces Rapid and Transient Membrane Blebbing in U373MG Cells in a p21-Activated Kinase-Dependent Manner

U373MG astrocytoma cells endogenously express the full-length neurokinin 1 receptor (NK1R). Substance P (SP), the natural ligand for NK1R, triggers rapid and transient membrane blebbing and we report that these morphological changes have different dynamics and intracellular signaling as compared to...

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Main Authors: Meshki, John, Douglas, Steven D., Hu, Mingyue, Leeman, Susan E., Tuluc, Florin
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179504/
https://ncbi.nlm.nih.gov/pubmed/21966499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025332
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