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A Naturally Occurring Isoform Inhibits Parathyroid Hormone Receptor Trafficking and Signaling
Parathyroid hormone (PTH) regulates calcium homeostasis and bone remodeling through its cognitive receptor (PTHR). We describe here a PTHR isoform harboring an in-frame 42-bp deletion of exon 14 (Δe14-PTHR) that encodes transmembrane domain 7. Δe14-PTHR was detected in human kidney and buccal epithe...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wiley Subscription Services, Inc., A Wiley Company
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3179322/ https://ncbi.nlm.nih.gov/pubmed/20578167 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.167 |
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