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Inhibitory Effects of Megakaryocytic Cells in Prostate Cancer Skeletal Metastasis

Prostate cancer cells commonly spread through the circulation, but few successfully generate metastatic foci in bone. Osteoclastic cellular activity has been proposed as an initiating event for skeletal metastasis. Megakaryocytes (MKs) inhibit osteoclastogenesis, which could have an impact on tumor...

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Detalhes bibliográficos
Main Authors: Li, Xin, Koh, Amy J, Wang, Zhengyan, Soki, Fabiana N, Park, Serk In, Pienta, Kenneth J, McCauley, Laurie K
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179321/
https://ncbi.nlm.nih.gov/pubmed/20684002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.204
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