Squalamine as a broad-spectrum systemic antiviral agent with therapeutic potential

Antiviral compounds that increase the resistance of host tissues represent an attractive class of therapeutic. Here, we show that squalamine, a compound previously isolated from the tissues of the dogfish shark (Squalus acanthias) and the sea lamprey (Petromyzon marinus), exhibits broad-spectrum ant...

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Bibliografiska uppgifter
Huvudupphovsmän: Zasloff, Michael, Adams, A. Paige, Beckerman, Bernard, Campbell, Ann, Han, Ziying, Luijten, Erik, Meza, Isaura, Julander, Justin, Mishra, Abhijit, Qu, Wei, Taylor, John M., Weaver, Scott C., Wong, Gerard C. L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2011
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179074/
https://ncbi.nlm.nih.gov/pubmed/21930925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1108558108
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