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Helicobacter pylori vacuolating cytotoxin A (VacA) engages the mitochondrial fission machinery to induce host cell death

A number of pathogenic bacteria target mitochondria to modulate the host's apoptotic machinery. Studies here revealed that infection with the human gastric pathogen Helicobacter pylori disrupts the morphological dynamics of mitochondria as a mechanism to induce host cell death. The vacuolating...

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Detalhes bibliográficos
Main Authors: Jain, Prashant, Luo, Zhao-Qing, Blanke, Steven R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179038/
https://ncbi.nlm.nih.gov/pubmed/21903925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1105175108
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