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Synthesis, Antiviral and Cytotoxic Activities of 2-(2-Phenyl carboxylic acid)-3-Phenylquinazolin -4(3H)-one Derivatives

A series of novel 2,3-disubstitutedquinazolin-4(3H)-ones have been synthesized by condensation of 2-substituted benzo[1,3]oxazine-4-ones and anthranilic acid. Synthesized compounds were evaluated for in vitro antiviral activity against HIV, HSV and vaccinia viruses. 5-Bromo-2-(6-bromo-4-oxo-2-phenyl...

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Detalhes bibliográficos
Main Authors: Selvam, P., Murugesh, N., Chandramohan, M., Pannecouque, C., DE Clercq, E.
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3178989/
https://ncbi.nlm.nih.gov/pubmed/21969760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0250-474X.84603
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