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The Insertion of Fluorescent Proteins in a Variable Region of Respiratory Syncytial Virus L Polymerase Results in Fluorescent and Functional Enzymes But with Reduced Activities

The respiratory syncytial virus (RSV) Large protein L is the catalytic subunit of the RNA-dependent RNA polymerase complex. Currently, no structural information is available for RSV L. Sequence alignments of L protein from human and bovine strains of RSV revealed the existence of two variable region...

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Autores principales: Fix, Jenna, Galloux, Marie, Blondot, Marie-Lise, Eléouët, Jean-François
Formato: Artigo
Lenguaje:Inglês
Publicado: Bentham Open 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3178903/
https://ncbi.nlm.nih.gov/pubmed/21966341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1874357901105010103
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