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Chemical Biology of Lysine Demethylases

Abnormal levels of DNA methylation and/or histone modifications are observed in patients with a wide variety of chronic diseases. Methylation of lysines within histone tails is a key modification that contributes to increased gene expression or repression depending on the specific residue and degree...

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Bibliographic Details
Main Author: Heightman, Tom D
Format: Artigo
Language:Inglês
Published: Bentham Open 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3178875/
https://ncbi.nlm.nih.gov/pubmed/21966346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1875397301005010062
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