Subunit Compensation and Plasticity of Synaptic GABA(A) Receptors Induced by Ethanol in α4 Subunit Knockout Mice

There is considerable evidence that ethanol (EtOH) potentiates γ-aminobutyric acid type A receptor (GABA(A)R) action, but only GABA(A)Rs containing δ subunits appear sensitive to low millimolar EtOH. The α4 and δ subunits co-assemble into GABA(A)Rs which are relatively highly expressed at extrasynap...

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Detalhes bibliográficos
Main Authors: Suryanarayanan, Asha, Liang, Jing, Meyer, Edward M., Lindemeyer, A. Kerstin, Chandra, Dev, Homanics, Gregg E., Sieghart, Werner, Olsen, Richard W., Spigelman, Igor
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2011
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3178803/
https://ncbi.nlm.nih.gov/pubmed/21977012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2011.00110
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