Deficient of a Clock Gene, Brain and Muscle Arnt-Like Protein-1 (BMAL1), Induces Dyslipidemia and Ectopic Fat Formation

A link between circadian rhythm and metabolism has long been discussed. Circadian rhythm is controlled by positive and negative transcriptional and translational feedback loops composed of several clock genes. Among clock genes, the brain and muscle Arnt-like protein-1 (BMAL1) and circadian locomoto...

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Hauptverfasser: Shimba, Shigeki, Ogawa, Tomohiro, Hitosugi, Shunsuke, Ichihashi, Yuya, Nakadaira, Yuki, Kobayashi, Munehiro, Tezuka, Masakatsu, Kosuge, Yasuhiro, Ishige, Kumiko, Ito, Yoshihisa, Komiyama, Kazuo, Okamatsu-Ogura, Yuko, Kimura, Kazuhiro, Saito, Masayuki
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3178629/
https://ncbi.nlm.nih.gov/pubmed/21966465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025231
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