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Novel Interactions between Actin and the Proteasome Revealed by Complex Haploinsufficiency

Saccharomyces cerevisiae has been a powerful model for uncovering the landscape of binary gene interactions through whole-genome screening. Complex heterozygous interactions are potentially important to human genetic disease as loss-of-function alleles are common in human genomes. We have been using...

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Detalles Bibliográficos
Autores principales: Haarer, Brian, Aggeli, Dimitra, Viggiano, Susan, Burke, Daniel J., Amberg, David C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3178594/
https://ncbi.nlm.nih.gov/pubmed/21966278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002288
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