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Galectin-3 Facilitates Cell Motility in Gastric Cancer by Up-Regulating Protease-Activated Receptor-1(PAR-1) and Matrix Metalloproteinase-1(MMP-1)

BACKGROUND: Galectin-3 is known to regulate cancer metastasis. However, the underlying mechanism has not been defined. Through the DNA microarray studies after galectin-3 silencing, we demonstrated here that galectin-3 plays a key role in up-regulating the expressions of protease-activated receptor-...

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Bibliografiske detaljer
Main Authors: Kim, Seok-Jun, Shin, Ji-Young, Lee, Kang-Duck, Bae, Young-Ki, Choi, Il-Ju, Park, Seok Hee, Chun, Kyung-Hee
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3178590/
https://ncbi.nlm.nih.gov/pubmed/21966428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025103
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