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A Mycobacterium leprae Hsp65 Mutant as a Candidate for Mitigating Lupus Aggravation in Mice

Hsp60 is an abundant and highly conserved family of intracellular molecules. Increased levels of this family of proteins have been observed in the extracellular compartment in chronic inflammation. Administration of M. leprae Hsp65 [WT] in [NZBxNZW]F(1) mice accelerates the Systemic Lupus Erythemato...

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Autors principals: Marengo, Eliana B., de Moraes, Luciana V., Melo, Robson L., Balan, Andrea, Fernandes, Beatriz L., Tambourgi, Denise V., Rizzo, Luiz Vicente, Sant'Anna, Osvaldo Augusto
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3178518/
https://ncbi.nlm.nih.gov/pubmed/21961033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024093
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