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In vitro transcription analysis of the role of flanking sequence on the DNA sequence specificity of adriamycin.
An in vitro transcription assay has been used to define twelve high occupancy transcriptional blockage sites in 260 bp of heterogenous DNA on three promoter-containing DNA fragments. Transcription proceeded to immediately upstream of CpA sequences in nine of these sites, and this defines the most pr...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
1989
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| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC317849/ https://ncbi.nlm.nih.gov/pubmed/2660099 |
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