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Nuclear relocalisation of cytoplasmic poly(A)-binding proteins PABP1 and PABP4 in response to UV irradiation reveals mRNA-dependent export of metazoan PABPs

Poly(A)-binding protein 1 (PABP1) has a fundamental role in the regulation of mRNA translation and stability, both of which are crucial for a wide variety of cellular processes. Although generally a diffuse cytoplasmic protein, it can be found in discrete foci such as stress and neuronal granules. M...

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Detalhes bibliográficos
Principais autores: Burgess, Hannah M., Richardson, William A., Anderson, Ross C., Salaun, Christine, Graham, Sheila V., Gray, Nicola K.
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3178455/
https://ncbi.nlm.nih.gov/pubmed/21940797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.087692
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