GLUT2 Accumulation in Enterocyte Apical and Intracellular Membranes: A Study in Morbidly Obese Human Subjects and ob/ob and High Fat–Fed Mice

OBJECTIVE: In healthy rodents, intestinal sugar absorption in response to sugar-rich meals and insulin is regulated by GLUT2 in enterocyte plasma membranes. Loss of insulin action maintains apical GLUT2 location. In human enterocytes, apical GLUT2 location has not been reported but may be revealed u...

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Detalhes bibliográficos
Main Authors: Ait-Omar, Amal, Monteiro-Sepulveda, Milena, Poitou, Christine, Le Gall, Maude, Cotillard, Aurélie, Gilet, Jules, Garbin, Kevin, Houllier, Anne, Château, Danièle, Lacombe, Amélie, Veyrie, Nicolas, Hugol, Danielle, Tordjman, Joan, Magnan, Christophe, Serradas, Patricia, Clément, Karine, Leturque, Armelle, Brot-Laroche, Edith
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2011
Assuntos:
Pathophysiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3178286/
https://ncbi.nlm.nih.gov/pubmed/21852673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-1740
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