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Enamel Pathology Resulting from Loss of Function in the Cystic Fibrosis Transmembrane Conductance Regulator in a Porcine Animal Model

Cystic fibrosis (CF) is caused by mutations in the gene encoding the CF transmembrane conductance regulator (CFTR), a phosphorylation- and ATP-regulated anion channel. CFTR expression and activity is frequently associated with an anion exchanger (AE) such as AE2 coded by the Slc4a2 gene. Mice null f...

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Bibliografiske detaljer
Main Authors: Chang, Eugene H., Lacruz, Rodrigo S., Bromage, Timothy G., Bringas, Pablo, Welsh, Michael J., Zabner, Joseph, Paine, Michael L.
Format: Artigo
Sprog:Inglês
Udgivet: S. Karger AG 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3178086/
https://ncbi.nlm.nih.gov/pubmed/21525720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000324248
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