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Apo- and holo-lactoferrin are both internalized by lactoferrin receptor via clathrin-mediated endocytosis but differentially affect ERK-signaling and cell proliferation in Caco-2 cells

Lactoferrin (Lf) is a major iron-binding and multi-functional protein in exocrine fluids such as breast milk and mucosal secretions. The functions of Lf appear dependent upon the iron-saturation of the Lf protein and are postulated to be mediated through Lf internalization by a Lf receptor (LfR). Ho...

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Detaylı Bibliyografya
Asıl Yazarlar: Jiang, Rulan, Lopez, Veronica, Kelleher, Shannon L., Lönnerdal, Bo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3178039/
https://ncbi.nlm.nih.gov/pubmed/21935933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.22650
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