Mice with null mutation of Ceacam1 develop nonalcoholic steatohepatitis

Transgenic liver-specific inactivation of the carcinoembryonic antigen-related cell adhesion molecule (CEACAM1) impairs hepatic insulin clearance and causes hyperinsulinemia, insulin resistance, elevation in hepatic and serum triglyceride levels, and visceral obesity. It also predisposes to nonalcho...

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Main Authors: Ghosh, Sumona, Kaw, Meenakshi, Patel, Payal R, Ledford, Kelly J, Bowman, Thomas A, McInerney, Marcia F, Erickson, Sandra K, Bourey, Raymond E, Najjar, Sonia M
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2010
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3177946/
https://ncbi.nlm.nih.gov/pubmed/21949477
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