Elevated citrate in pediatric astrocytomas with malignant progression

In vivo magnetic resonance spectroscopy (MRS) provides information about metabolite concentrations in tissue. Recently citrate was detected by MRS in subgroups of pediatric brain tumors. Citrate is an intermediate in the tricarboxylic acid (TCA) cycle and accumulates in tissue when the glycolytic ra...

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Bibliographic Details
Main Authors: Blüml, Stefan, Panigrahy, Ashok, Laskov, Mikhail, Dhall, Girish, Krieger, Mark D., Nelson, Marvin D., Finlay, Jonathan L., Gilles, Floyd H.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2011
Subjects:
Basic and Translational Investigations
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3177657/
https://ncbi.nlm.nih.gov/pubmed/21771868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nor087
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