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Ketamine Disrupts Theta Modulation of Gamma in a Computer Model of Hippocampus

Abnormalities in oscillations have been suggested to play a role in schizophrenia. We studied theta-modulated gamma oscillations in a computer model of hippocampal CA3 in vivo with and without simulated application of ketamine, an NMDA receptor antagonist and psychotomimetic. Networks of 1200 multic...

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Autors principals: Neymotin, Samuel A., Lazarewicz, Maciej T., Sherif, Mohamed, Contreras, Diego, Finkel, Leif H., Lytton, William W.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3177405/
https://ncbi.nlm.nih.gov/pubmed/21832203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0501-11.2011
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