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Cholinergic Autoantibodies from Primary Sjögren's Syndrome Inhibit Mucin Production via Phospholipase C and Cyclooxygenase-2 In the Rat Submandibular Gland

BACKGROUND: Patients with primary Sjögren's syndrome (pSS) produce functional IgG against cholinoreceptor of exocrine glands modifying their activity. The aim of the present work was to demonstrate pSS IgG antibodies (pSS IgG) interacting with M(3) muscarinic acetylcholine receptors (mAChR) of...

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Detalhes bibliográficos
Main Authors: Passafaro, Daniela, Sterin-Borda, Leonor, Reina, Silvia, Borda, Enri
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications Pvt Ltd 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3177389/
https://ncbi.nlm.nih.gov/pubmed/22013477
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