Cholinergic Autoantibodies from Primary Sjögren's Syndrome Inhibit Mucin Production via Phospholipase C and Cyclooxygenase-2 In the Rat Submandibular Gland

BACKGROUND: Patients with primary Sjögren's syndrome (pSS) produce functional IgG against cholinoreceptor of exocrine glands modifying their activity. The aim of the present work was to demonstrate pSS IgG antibodies (pSS IgG) interacting with M(3) muscarinic acetylcholine receptors (mAChR) of...

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Bibliografski detalji
Glavni autori: Passafaro, Daniela, Sterin-Borda, Leonor, Reina, Silvia, Borda, Enri
Format: Artigo
Jezik:Inglês
Izdano: Medknow Publications Pvt Ltd 2011
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Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3177389/
https://ncbi.nlm.nih.gov/pubmed/22013477
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