Temporally controlled modulation of FGF/ERK signaling directs midbrain dopaminergic neural progenitor fate in mouse and human pluripotent stem cells

Effective induction of midbrain-specific dopamine (mDA) neurons from stem cells is fundamental for realizing their potential in biomedical applications relevant to Parkinson’s disease. During early development, the Otx2-positive neural tissues are patterned anterior-posteriorly to form the forebrain...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Jaeger, Ines, Arber, Charles, Risner-Janiczek, Jessica R., Kuechler, Judit, Pritzsche, Diana, Chen, I-Cheng, Naveenan, Thulasi, Ungless, Mark A., Li, Meng
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2011
Assuntos:
Development and Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3177308/
https://ncbi.nlm.nih.gov/pubmed/21880784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.066746
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados